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KMID : 0390220070180010100
Journal of Clinical Otolaryngology, Head and Neck Surgery
2007 Volume.18 No. 1 p.100 ~ p.103
A Case of Langerhans Cell Histiocytosis with Sequential
Jeong Eul-Hyun

Han Chi-Sung
Oh Jae-Gyu
Lee Won-Yong
Abstract
Langerhans cell histiocytosis is a rare disorder characterized by a proliferation of abnormal and clonal Langerhans
cells. It can involve bone, skin, lymph node, viscera, but skull involvement is the most common. The clinical
spectrum of disease is quite varied, ranging from a solitary eosinophilic granuloma to diffuse multisystem involvement.
We present a case of Langerhans cell histiocytosis in a 2-year-old female with left tibia and bilateral
temporal bone involvement sequentially at an interval of 2 years.
KEYWORD
Langerhans cell histiocytosis, Temporal bone
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